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George E. Taffet, MD, FGSA (he/him/his)

Professor
Houston Methodist Hospital
Houston, Texas, United States

I was at Baylor College of Medicine from 1982 (for my internal medicine training, clinical Geriatrics fellowship, fellowship in cardiovascular research and on the faculty) until 2024. At Baylor I taught the aging lectures in ARTS (age-related themes) for twenty years as the culmination of the didactic experience in the medical student’s second year, and provided clinical opportunities to learn from and about old people all across the care spectrum. This includes house calls, independent living facilities, nursing homes, the hospital and the hospice. I teach Baylor Geriatrics fellows, and Methodist medicine residents as an Attending Physician, in conferences, and at the VA and Methodist morning report. I am also a faculty member in the Huffington Center of Aging Biology of Aging Graduate Program, the Physiology Graduate Program, and the Translational Biology and Molecular Medicine Graduate Program.
My research interests have been in the area of aging physiology especially cardiovascular aging and Heart failure with Preserved Ejection Fraction. My early interests centered on aging and endurance exercise training for rats and how exercise improved the heart's ability to fill, its diastolic function. I have remained interested in diastole as heart failure due to diastolic dysfunction as the most common type of heart failure for older people, impacting their quality of life and survival. Our approach is to address the underlying aging change that is additive to any disease mediated changes. Additionally, as our group has developed many of the techniques to assess cardiac function in mice, we are a resource to a number of investigators across the Texas Medical Center. However, my goal is clearly to improve the condition of the older people through clinical teaching, and issues that underscore the physiologic changes that occur with age, like delirium.

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