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Patricia Opresko, PhD

Professor
University of Pittsburgh
Pittsburgh, Pennsylvania, United States

Dr. Patricia L. Opresko is a tenured Professor in the Department of Environmental and Occupational Health at the University of Pittsburgh School of Public Health. She holds a secondary appointment in the Department of Pharmacology and Chemical Biology at the School of Medicine. Patty is Co-Leader of the Genome Stability Program at the UPMC Hillman Cancer Center and a member of the Center for Nucleic Acid Science and Technology at Carnegie Mellon University. She received her PhD from the Pennsylvania State University College of Medicine in Biochemistry and Molecular Biology. Patty started her laboratory at Pitt in 2005. Her lab investigates the mechanisms of genomic and telomere instability associated with aging and cancer. She studies how environmental genotoxic and oxidative stress accelerate telomere shortening, and the role of DNA damage and repair in telomere maintenance. Patty is currently a principal investigator on an R35 RIVER grant from the National Institute of Environmental Health Sciences and co-PI on a National Cancer Institute R01 grant. Patty is internationally recognized for her work in genome stability, telomere biology and DNA repair, and published over 100 peer-reviewed manuscripts. She is an Associate Editor for the journal DNA Repair, and has served on numerous review panels of research proposals for NIH and other organizations. Patty was elected to Chair the 2023 Gordon Research Conference on Mammalian DNA Repair, and she currently serves as elected President of the Environmental Mutagenesis and Genomics Society. She has been invited frequently to deliver scientific seminars, and received numerous awards including the Glenn Award for Research in Biological Mechanisms of Aging (2019) and the Merrill J. Egorin Excellence in Scientific Leadership Award (2020). She is greatly involved in graduate and post-doctoral mentoring across several departments at Pitt and lectures in Human Genetics, Biology of Aging and DNA Repair graduate courses.

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